What can we learn from Yusuf's case?
Liposomal Amphotericin B has demonstrated
reduced nephrotoxicity vs. other amphotericin
B formulations*,**1,13–20
Early suspicion may help to prevent mortality28
Liposomal Amphotericin B has a broad-
spectrum of activity against most clinically-
relevant fungal pathogens23,24,30,31
When facing life-threatening IFIs in the ICU
treat promptly and broad with Liposomal
Amphotericin B.1,2,23,24,30,31
In this case, potential toxicity was a key consideration
when treatment decisions were made, especially
given the patient’s history of liver disease and initial
acute renal failure.
Diagnosis of IFIs in patients admitted to the ICU is
particularly challenging, and waiting for conclusive
results may lead to a delay in treatment initiation.4,29
The timely initiation of an appropriate antifungal
therapy may be essential for your patients' survival.2,23
Liposomal Amphotericin B demonstrates fungicidal
activity against Aspergillus fumigatus and Aspergillus
flavus.25
*Please refer to the Summary of Product Characteristics of your chosen
treatment prior to prescribing.
**Renal adverse reactions may still occur.
Close monitoring of patient electrolytes and renal
function during Liposomal Amphotericin B treatment
is important, especially at escalated doses.1,27
Liposomal Amphotericin B has demonstrated reduced nephrotoxicity vs. other amphotericin B
formulations*,**1,13–20
Early suspicion may help to prevent mortality28
Liposomal Amphotericin B has a broad-spectrum of activity against most clinically-relevant fungal
pathogens23,24,30,31
When facing life-threatening IFIs in the ICU treat promptly and broad with
Liposomal Amphotericin B.1,2,23,24,30,31
In this case, potential toxicity was a key consideration when treatment decisions were made, especially given the patient’s history of liver
disease and initial acute renal failure.
Close monitoring of patient electrolytes and renal function during Liposomal Amphotericin B treatment is important, especially at escalated doses.1,27
Diagnosis of IFIs in patients admitted to the ICU is particularly challenging, and waiting for conclusive results may lead to a delay in
treatment initiation.4,29 The timely initiation of an appropriate antifungal therapy may be essential for your patients' survival.2,23
*Please refer to the Summary of Product Characteristics of your chosen treatment prior to prescribing.
**Renal adverse reactions may still occur.
Liposomal Amphotericin B demonstrates fungicidal activity against Aspergillus fumigatus and Aspergillus flavus.25
What can we learn from Yusuf's case?